Canker sores treatments differ by severity because minor sores heal naturally in 1-2 weeks with basic pain relief, while major sores demand aggressive interventions like steroids or lasers to manage deeper tissue damage, scarring risk, and eating interference. Classification guides therapy from OTC rinses (small ulcers) to systemic medications (recurrent/large lesions exceeding 1cm).
Minor Canker Sores (Under 1cm)
Smallest/most common (85% cases), oval-shaped with red borders, cause mild pain 3-5 days resolving in 7-14 days without scarring. OTC hydrogen peroxide rinses, benzocaine gels (Orajel), or salt water soothes irritation; avoid irritants like acidic foods.
Major Canker Sores (Over 1cm)
Rare (10% cases), deep/round ulcers >1cm cause severe pain, fever, lymph swelling, lasting 4-6 weeks with scarring risk. Prescription steroid pastes (triamcinolone 0.1%, clobetasol 0.05% gel) reduce inflammation; silver nitrate or laser cauterization destroys tissue accelerating closure.
Herpetiform Canker Sores (Multiple Tiny Ulcers)
50+ pinpoint sores cluster creating broad inflamed areas; heal 1-2 weeks but recur frequently. Antiseptic rinses (chlorhexidine) prevent secondary infection; low-dose steroids if immune-mediated.
Factors Dictating Treatment Escalation
Pain interfering with eating/speaking, duration >2 weeks, sores >1cm, or recurrence >3x/year trigger prescription care. Bacterial superinfection (pus/fever) requires antibiotics alongside steroids.
Systemic/Recurrent Cases
Underlying conditions (Behçet’s, vitamin B12/iron deficiency, celiac) cause complex aphthae needing bloodwork/oral steroids (prednisone). Colchicine/sucralfate protect mucosa in refractory patients.
Conclusion
Severity determines canker sore treatment through ulcer size (>1cm), depth (scarring risk), pain level (eating interference), and recurrence frequency (underlying pathology). Minor self-resolve; major/recurrent demand prescription escalation.
FAQs
Minor canker sore maximum size before escalation?
Under 1cm, oval, heals 7-14 days; >1cm/round/deep signals major requiring steroids.
Major canker sore healing timeline untreated?
4-6 weeks with scarring; prescription steroids reduce to 1-2 weeks.
OTC pain relief duration limits?
Benzocaine/Orajel safe 7 days max; persistent pain needs prescription steroid rinse.
When do herpetiform sores need systemic treatment?
20 ulcers, recurrence monthly, or nutritional deficiencies confirmed via bloodwork.
Laser vs chemical cauterization differences?
Laser sterilizes/seals instantly (office procedure); silver nitrate destroys tissue chemically (OTC/professional).
Fever with canker sores indicates what?
Major sores or bacterial superinfection—seek antibiotics alongside steroids.
Vitamin therapy effectiveness timeline?
B12/iron supplements reduce recurrence 50% within 3 months if deficient; test first.
Acidic foods restriction duration?
Avoid 48 hours post-onset until pain subsides; resume gradually.
Mouthwash frequency for multiple sores?
Chlorhexidine 2x daily 7 days prevents infection without staining if diluted.
Recurrent aphthae (>4/year) first diagnostic step?
Bloodwork for B12, ferritin, celiac antibodies; biopsy if Behçet’s suspected.



